Gastritis disease is almost a disease of women and children, the disease regardless of age, usually do not pay attention to their diet, overeating, or pay attention to health, etc., will suffer from gastritis disease, so, in peacetime, we should pay attention These questions, the following we have to carefully understand the pathogenesis of gastritis.
Acute gastritis etiology
Can be caused by chemical factors, physical factors, microbial infection or bacterial toxins. In addition, mental neurological dysfunction, stress or a variety of factors due to organism allergy can be used as endogenous stimulating factor, causing acute inflammation of gastric mucosa damage.
Chronic etiology of chronic gastritis
Hp infection has been clear as the most important cause of chronic gastritis, it was called Hp-related gastritis. But other physical, chemical and biological harmful factors long-term repeated effects on the susceptible body can also cause the disease. The etiology of persistent or recurring can form chronic lesions. In the rural areas of Finland with a random sampling method for gastric mucosal examination, confirmed that chronic atrophic gastritis is a chronic progressive lesions of superficial inflammation of the first become irreversible atrophic inflammation. There is also evidence from the clinical observation of this problem. Young people mostly superficial gastritis, the elderly mostly atrophic gastritis; superficial gastritis and atrophic gastritis often exist in the same patient; another retrospective gastric mucosa biopsy also found that part of the superficial gastritis for several years Later become atrophic gastritis is currently considered chronic gastritis is caused by a variety of factors.
Helicobacter pylori infection: 1982 Marshall and Warren first isolated a micro-anoxic, catalase positive, with urease activity of Gram-negative spirochete, 3μm × 0.5μm size, was curved or S-shaped end of 2 ~ 6 sheaths with sheaths. 95% of active gastritis has this bacterial infection, initially named as Campylobacter Microorganisms (CLO), later renamed pyramid pylori (pylobacter pylori), in 1989 according to its biochemical and morphological characteristics once again renamed Helicobacter pylori ( figure 1). We confirmed that Hp in chronic active gastritis detection rate of 98% to 100%, indicating that chronic gastritis, especially chronic active gastritis and Hp infection is closely related. 1985 Marshall, 1987 Morris two themselves as a volunteer oral Hp caused acute gastritis, cured by antibiotics. 1987 Lam bert successfully established the animal model of Hp gastritis with suckling pig so that Hp has basically conformed to Koch's criteria for pathogens.
Experts pointed out that the etiology of chronic gastritis clinical practice has not yet fully elucidated, is generally believed that the surrounding environment with the harmful factors and susceptible to physical. Physical, chemical, biological harmful factors long-term repeated role in the susceptible body can cause the disease. Chronic gastritis can occur repeatedly to form chronic lesions.
1. Long-term use of drugs to stimulate the stomach, food and eating rough food or smoking. These factors repeatedly act on the gastric mucosa, so that congestion and edema.
2. long-term gastric congestion and hypoxia. Such as congestive heart failure or portal hypertensive patients, gastric mucosa for a long time in the congestion, hypoxia, causing nutritional disorders lead to gastritis.
3. Acute gastritis such as improper treatment, delayed healing can be transformed into chronic gastritis.
4. Gastric acid deficiency, bacteria easily spread in the stomach, can also cause chronic gastritis.
5. Nutritional deficiency, endocrine dysfunction, immune dysfunction, can cause chronic gastritis.
6. Pathogenic Campylobacter infection and so may be the risk of chronic gastritis factors.
7. The role of bacteria and their toxins. Due to the nose, mouth, throat and other parts of the infection of bacteria or toxins continue to be swallowed into the stomach; or stomach lack of gastric acid, bacteria in the stomach breeding, long-term effects caused by chronic gastritis.
8. Mental factors. Excessive mental stimulation, depression and other mental factors repeatedly in the cerebral cortex, resulting in cerebral cortex dysfunction, leading to gastric spasm of the contraction of blood vessels, gastric mucosal inflammation or ulcers.
Third, the etiology of verrucous gastritis
Macroscopic lesions were characterized by verrucous uplift, but also showed no plastic or long strip, color and mucous membrane similar to the surrounding. Lesions are mostly distributed in the antrum, can also be distributed in the stomach and stomach, often along the folds ridge was chain arrangement, diameter of about 0.5-1.5cm, high 0.2-0.5cm. The top of the uplift is umbilical depressive erosive, light red or with yellow thin moss. Histology is divided into erosion and repair period.
Agglomeration histological features of epithelial degeneration, necrosis and shedding, neutrophil infiltration and a small amount of cellulose exudation, and sometimes visible superficial gland necrosis at the same time accompanied by pyloric gland or gastric small skin hyperplasia. The main performance of the repair period of this erosion around the inherent glands, pyloric gland or stomach pits epithelial hyperplasia, and sometimes visible fibrosis, regeneration of the duct can occur in varying degrees of atypical hyperplasia. Mucosal muscle layer is often thickened and uplift, structural disorders.
The above content is specially prepared for everyone on the etiology of gastritis related knowledge, I believe interested friends have also click on this article carefully read, and for the pathology of gastritis also mastered some knowledge, in this wish Everyone good mouth, body stick, no trouble.
Acute gastritis etiology
Can be caused by chemical factors, physical factors, microbial infection or bacterial toxins. In addition, mental neurological dysfunction, stress or a variety of factors due to organism allergy can be used as endogenous stimulating factor, causing acute inflammation of gastric mucosa damage.
Chronic etiology of chronic gastritis
Hp infection has been clear as the most important cause of chronic gastritis, it was called Hp-related gastritis. But other physical, chemical and biological harmful factors long-term repeated effects on the susceptible body can also cause the disease. The etiology of persistent or recurring can form chronic lesions. In the rural areas of Finland with a random sampling method for gastric mucosal examination, confirmed that chronic atrophic gastritis is a chronic progressive lesions of superficial inflammation of the first become irreversible atrophic inflammation. There is also evidence from the clinical observation of this problem. Young people mostly superficial gastritis, the elderly mostly atrophic gastritis; superficial gastritis and atrophic gastritis often exist in the same patient; another retrospective gastric mucosa biopsy also found that part of the superficial gastritis for several years Later become atrophic gastritis is currently considered chronic gastritis is caused by a variety of factors.
Helicobacter pylori infection: 1982 Marshall and Warren first isolated a micro-anoxic, catalase positive, with urease activity of Gram-negative spirochete, 3μm × 0.5μm size, was curved or S-shaped end of 2 ~ 6 sheaths with sheaths. 95% of active gastritis has this bacterial infection, initially named as Campylobacter Microorganisms (CLO), later renamed pyramid pylori (pylobacter pylori), in 1989 according to its biochemical and morphological characteristics once again renamed Helicobacter pylori ( figure 1). We confirmed that Hp in chronic active gastritis detection rate of 98% to 100%, indicating that chronic gastritis, especially chronic active gastritis and Hp infection is closely related. 1985 Marshall, 1987 Morris two themselves as a volunteer oral Hp caused acute gastritis, cured by antibiotics. 1987 Lam bert successfully established the animal model of Hp gastritis with suckling pig so that Hp has basically conformed to Koch's criteria for pathogens.
Experts pointed out that the etiology of chronic gastritis clinical practice has not yet fully elucidated, is generally believed that the surrounding environment with the harmful factors and susceptible to physical. Physical, chemical, biological harmful factors long-term repeated role in the susceptible body can cause the disease. Chronic gastritis can occur repeatedly to form chronic lesions.
1. Long-term use of drugs to stimulate the stomach, food and eating rough food or smoking. These factors repeatedly act on the gastric mucosa, so that congestion and edema.
2. long-term gastric congestion and hypoxia. Such as congestive heart failure or portal hypertensive patients, gastric mucosa for a long time in the congestion, hypoxia, causing nutritional disorders lead to gastritis.
3. Acute gastritis such as improper treatment, delayed healing can be transformed into chronic gastritis.
4. Gastric acid deficiency, bacteria easily spread in the stomach, can also cause chronic gastritis.
5. Nutritional deficiency, endocrine dysfunction, immune dysfunction, can cause chronic gastritis.
6. Pathogenic Campylobacter infection and so may be the risk of chronic gastritis factors.
7. The role of bacteria and their toxins. Due to the nose, mouth, throat and other parts of the infection of bacteria or toxins continue to be swallowed into the stomach; or stomach lack of gastric acid, bacteria in the stomach breeding, long-term effects caused by chronic gastritis.
8. Mental factors. Excessive mental stimulation, depression and other mental factors repeatedly in the cerebral cortex, resulting in cerebral cortex dysfunction, leading to gastric spasm of the contraction of blood vessels, gastric mucosal inflammation or ulcers.
Third, the etiology of verrucous gastritis
Macroscopic lesions were characterized by verrucous uplift, but also showed no plastic or long strip, color and mucous membrane similar to the surrounding. Lesions are mostly distributed in the antrum, can also be distributed in the stomach and stomach, often along the folds ridge was chain arrangement, diameter of about 0.5-1.5cm, high 0.2-0.5cm. The top of the uplift is umbilical depressive erosive, light red or with yellow thin moss. Histology is divided into erosion and repair period.
The above content is specially prepared for everyone on the etiology of gastritis related knowledge, I believe interested friends have also click on this article carefully read, and for the pathology of gastritis also mastered some knowledge, in this wish Everyone good mouth, body stick, no trouble.
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