(3) metal contact (4) radiation (5) iron deficiency anemia (6) biological factors (3) 7) Physical factors (8) Bile or duodenal reflux (9) Immune factors (10) Helicobacter pylori (HP) infection
What are the pathogenic factors of gastritis? Gastritis is a very common disease, ten people have nine people have gastritis. It is a chronic disease in the drug treatment at the same time also pay attention to some of the details of life, because the stomach is the third rule, seven raise, if you do not pay attention to diet, treatment is no matter how good, always repeated Cure, there will be cancer may be.
(1) the continuation of chronic superficial gastritis: chronic atrophic gastritis can be developed from chronic superficial gastritis, the PLA General Hospital and other six hospitals reported 5 to 8 years follow-up observation of superficial gastritis 164 cases, of which 34 Cases into chronic atrophic gastritis (20.7%), the cause of chronic superficial gastritis can become chronic atrophic gastritis pathogenesis and aggravating factors.
(2) Genetic factors: According to the Varis survey, the incidence of chronic atrophic gastritis was significantly higher in the first generation of relatives of patients with chronic atrophic gastritis, and the genetic factors of malignant anemia were also significant. The incidence of relatives was higher than that of the control group 20 times larger, indicating that chronic atrophic gastritis may be related to genetic factors.
(3) metal contact: lead workers high incidence of gastric ulcer, gastric mucosal biopsy found that the incidence of atrophic gastritis is also increased, Polmer called excretion of gastritis, in addition to lead outside a lot of heavy metals such as mercury, tellurium, copper and Zinc and other gastric mucosa have a certain damage.
(4) radiation: radiation therapy ulcer disease or other tumors, can cause gastric mucosal injury or even atrophy.
(5) iron deficiency anemia: a lot of facts show that iron deficiency anemia and atrophic gastritis are closely related, Badanoch reported iron deficiency anemia in 50 cases, normal gastric mucosa, superficial gastritis and atrophic gastritis accounted for 14%, 46% And 40%, but the mechanism of anemia caused by gastritis is still unknown, some scholars believe that gastritis is the primary disease, because the stomach acid low iron can not absorb, or because of gastric bleeding and thus the formation of anemia; another view that anemia, Lack of body iron to make the gastric mucosal renewal rate affected and prone to inflammation.
(6) biological factors: chronic infectious diseases such as hepatitis, tuberculosis and other effects on the stomach also attracted people's attention, chronic liver disease patients often have chronic gastritis symptoms and signs of gastric mucosal staining also confirmed in patients with hepatitis B gastric mucosal Hepatitis B virus antigen and antibody complex, Ruijin Hospital reported 91 cases of atrophic gastritis patients, 24 cases (26.4%) with chronic hepatitis, so chronic infectious diseases, especially chronic liver disease on the stomach is noteworthy.
(7) physical factors: clinical statistics show that the incidence of this disease was significantly positively correlated with age, the older, gastric mucosal function "resistance" is worse, vulnerable to external factors caused by damage.
(8) bile or duodenal reflux: due to pyloric sphincter dysfunction or gastric jejunum anastomosis, bile or duodenal fluid can flow back to the stomach, and damage the gastric mucosal barrier, prompting H? + And pepsin Anti-mucous membrane caused by a series of pathological changes, leading to chronic superficial gastritis, and can develop chronic atrophic gastritis.
(9) immune factors: atrophic gastritis, especially in patients with gastric gastritis blood, gastric juice or atrophic mucosal plasma cells, often can be found in parietal cell antibodies or internal factors antibodies, so that the autoimmune response is chronic atrophic Gastritis of the cause of the cause, in recent years found a small number of gastric antral gastritis patients have gastrin secretion of cell antibodies, it is a cell of special autoimmune antibodies, is Ig G, partial atrophic gastritis patients in vitro lymphocyte transformation test and leukocyte movement inhibition test Abnormal, suggesting that cellular immune response in the occurrence of atrophic gastritis also has important significance.
(10) Helicobacter pylori (HP) infection: 1983 Australian scholar Marshall and Warren from patients with chronic gastritis antral mucous layer and epithelial cells for the first time isolated HP, after many scholars on chronic gastritis patients conducted a large number of experimental studies 60% to 90% of patients with chronic gastritis in the gastric mucosa culture HP, and then found that the degree of HP infection and gastric mucosal inflammation was positively correlated with the 1986 World Gastroenterology Society at the eighth session of the HP infection is made One of the important causes of chronic gastritis.
These are the pathogenic factors of gastritis, hoping to help everyone, we have to develop good habits in daily life, to eat easy to digest nutritious food, do not eat cold, hard, spicy and exciting Food, do not drink, so that we can protect our gastric mucosa from stimulation, to promote its recovery.
What are the pathogenic factors of gastritis? Gastritis is a very common disease, ten people have nine people have gastritis. It is a chronic disease in the drug treatment at the same time also pay attention to some of the details of life, because the stomach is the third rule, seven raise, if you do not pay attention to diet, treatment is no matter how good, always repeated Cure, there will be cancer may be.
(1) the continuation of chronic superficial gastritis: chronic atrophic gastritis can be developed from chronic superficial gastritis, the PLA General Hospital and other six hospitals reported 5 to 8 years follow-up observation of superficial gastritis 164 cases, of which 34 Cases into chronic atrophic gastritis (20.7%), the cause of chronic superficial gastritis can become chronic atrophic gastritis pathogenesis and aggravating factors.
(2) Genetic factors: According to the Varis survey, the incidence of chronic atrophic gastritis was significantly higher in the first generation of relatives of patients with chronic atrophic gastritis, and the genetic factors of malignant anemia were also significant. The incidence of relatives was higher than that of the control group 20 times larger, indicating that chronic atrophic gastritis may be related to genetic factors.
(3) metal contact: lead workers high incidence of gastric ulcer, gastric mucosal biopsy found that the incidence of atrophic gastritis is also increased, Polmer called excretion of gastritis, in addition to lead outside a lot of heavy metals such as mercury, tellurium, copper and Zinc and other gastric mucosa have a certain damage.
(4) radiation: radiation therapy ulcer disease or other tumors, can cause gastric mucosal injury or even atrophy.
(5) iron deficiency anemia: a lot of facts show that iron deficiency anemia and atrophic gastritis are closely related, Badanoch reported iron deficiency anemia in 50 cases, normal gastric mucosa, superficial gastritis and atrophic gastritis accounted for 14%, 46% And 40%, but the mechanism of anemia caused by gastritis is still unknown, some scholars believe that gastritis is the primary disease, because the stomach acid low iron can not absorb, or because of gastric bleeding and thus the formation of anemia; another view that anemia, Lack of body iron to make the gastric mucosal renewal rate affected and prone to inflammation.
(6) biological factors: chronic infectious diseases such as hepatitis, tuberculosis and other effects on the stomach also attracted people's attention, chronic liver disease patients often have chronic gastritis symptoms and signs of gastric mucosal staining also confirmed in patients with hepatitis B gastric mucosal Hepatitis B virus antigen and antibody complex, Ruijin Hospital reported 91 cases of atrophic gastritis patients, 24 cases (26.4%) with chronic hepatitis, so chronic infectious diseases, especially chronic liver disease on the stomach is noteworthy.
(7) physical factors: clinical statistics show that the incidence of this disease was significantly positively correlated with age, the older, gastric mucosal function "resistance" is worse, vulnerable to external factors caused by damage.
(8) bile or duodenal reflux: due to pyloric sphincter dysfunction or gastric jejunum anastomosis, bile or duodenal fluid can flow back to the stomach, and damage the gastric mucosal barrier, prompting H? + And pepsin Anti-mucous membrane caused by a series of pathological changes, leading to chronic superficial gastritis, and can develop chronic atrophic gastritis.
(9) immune factors: atrophic gastritis, especially in patients with gastric gastritis blood, gastric juice or atrophic mucosal plasma cells, often can be found in parietal cell antibodies or internal factors antibodies, so that the autoimmune response is chronic atrophic Gastritis of the cause of the cause, in recent years found a small number of gastric antral gastritis patients have gastrin secretion of cell antibodies, it is a cell of special autoimmune antibodies, is Ig G, partial atrophic gastritis patients in vitro lymphocyte transformation test and leukocyte movement inhibition test Abnormal, suggesting that cellular immune response in the occurrence of atrophic gastritis also has important significance.
(10) Helicobacter pylori (HP) infection: 1983 Australian scholar Marshall and Warren from patients with chronic gastritis antral mucous layer and epithelial cells for the first time isolated HP, after many scholars on chronic gastritis patients conducted a large number of experimental studies 60% to 90% of patients with chronic gastritis in the gastric mucosa culture HP, and then found that the degree of HP infection and gastric mucosal inflammation was positively correlated with the 1986 World Gastroenterology Society at the eighth session of the HP infection is made One of the important causes of chronic gastritis.
These are the pathogenic factors of gastritis, hoping to help everyone, we have to develop good habits in daily life, to eat easy to digest nutritious food, do not eat cold, hard, spicy and exciting Food, do not drink, so that we can protect our gastric mucosa from stimulation, to promote its recovery.
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