Core tip: the incidence of gastritis associated with the following factors: (1) to chronic superficial gastritis (2) genetic factors (3) metal contact (4) radiation (5) iron deficiency anemia (6) biological factors (7) physical factors (8) bile or duodenal reflux (9 (10) immune factors) of Helicobacter pylori (HP) infection
What are the pathogenic factors of gastritis? Gastritis is a very common disease. In ten people, nine people have gastritis. It is a chronic disease in drug treatment at the same time we should pay attention to some details of life, because the stomach is three cent, seven points, if not pay attention to diet, treatment is also good no use, repeatedly cannot be cured, but also the possibility of cancer.
(1) to chronic superficial gastritis, chronic atrophic gastritis by chronic superficial gastritis and report, General Hospital of PLA 6 hospital after 5 to 8 years of follow-up observation of 164 cases of superficial gastritis, including 34 cases into chronic atrophic gastritis (20.7%), etiology can chronic superficial gastritis become chronic atrophic gastritis pathogenesis and aggravating factors.
Genetic factors: (2) according to the Varis survey, patients with chronic atrophic gastritis of the first generation among relatives, chronic atrophic gastritis significantly increased the incidence of genetic factors, pernicious anemia is also very obvious, is related to the incidence rate is 20 times larger than the control group, chronic atrophic gastritis may be related to genetic factors.
(3) metal contact: lead the incidence of gastric ulcer workers operation rate is high, the gastric mucosa biopsy found atrophic gastritis incidence also increased, Polmer called the excretion of gastritis, except Pb many heavy metals such as mercury, tellurium, copper and zinc have certain effect on gastric mucosal injury.
(4) radiation: radiation therapy, ulcers or other tumors can cause damage or even atrophy of the gastric mucosa.
(5) iron deficiency anemia: a lot of the fact that iron deficiency anemia associated with atrophic gastritis, 50 cases of Badanoch reported iron deficiency anemia, normal gastric mucosa, superficial gastritis and atrophic gastritis each accounted for 14%, 46% and 40%, but the mechanism that anaemia causes gastritis is unknown, some scholars think that gastritis is the primary disease, because of low acid gastritis induced by iron cannot absorb, or because of stomach bleeding resulting in anemia; the other is that the first because of the lack of body iron anemia, gastric mucosal update rate affected and prone to inflammation.
(6) biological factors: chronic infectious diseases such as hepatitis, tuberculosis and other effects on the stomach also attracted the attention of people, patients with chronic liver disease often have chronic gastritis symptoms and signs of gastric mucosa staining also confirmed the antigen antibody complex with the hepatitis B virus in patients with hepatitis B in the gastric mucosa, Ruijin hospital reported 91 cases of atrophy gastritis patients, 24 cases (26.4%) with chronic hepatitis, and chronic infectious disease especially in patients with chronic liver disease of the stomach is worthy of note.
(7) physical factors: clinical statistics showed that showed a significant positive correlation with the age of this disease, age, function of gastric mucous membrane resistance is poor, easily affected by external adverse factors caused by injury.
(8) bile or duodenal reflux due to pyloric sphincter dysfunction or gastric or duodenal anastomosis after bile liquid reflux to the stomach, and the damage of the gastric mucosal barrier, promote H? + and anti pepsin scattered to the mucosa and cause a series of pathological changes, resulting in chronic superficial gastritis and the development of chronic atrophic gastritis.
(9): immune factors in atrophic gastritis, especially gastric body gastritis with blood, gastric juice or pulp cells in mucosal atrophy, often can be found in parietal cell antibody or antibody, so that autoimmune reaction is related to the etiology of chronic atrophic gastritis, in recent years the minority of antral gastritis patients the gastrin secreting cell antibody, it is the special cell antibodies, Ig G, part of patients with atrophic gastritis in vitro lymphocyte transformation test and leukocyte migration inhibition test is abnormal, the cellular immune response has an important significance in occurrence of atrophic gastritis.
(10) of Helicobacter pylori (HP) infection: 1983 Australia scholar Marshall and Warren from patients with chronic gastritis and gastric antrum mucous layer of epithelial cells was isolated from the HP, since then many scholars have conducted a lot of experimental research on patients with chronic gastritis, develop HP in 60% to 90% of patients with chronic gastric inflammation in gastric mucosa then, find the degree of infection was positively correlated with the severity of gastric mucosal inflammation related to the HP, the 1986 World Gastroenterological Association eighth session has proposed a HP infection is an important cause of chronic gastritis.
These are the pathogenic factors of gastritis, we hope to help, we also develop good eating habits in daily life, to eat digestible nutritious food, do not eat cold, hard, spicy spicy food, do not drink, so that we can protect our stomach mucosa irritation, promote its recovery.
What are the pathogenic factors of gastritis? Gastritis is a very common disease. In ten people, nine people have gastritis. It is a chronic disease in drug treatment at the same time we should pay attention to some details of life, because the stomach is three cent, seven points, if not pay attention to diet, treatment is also good no use, repeatedly cannot be cured, but also the possibility of cancer.
(1) to chronic superficial gastritis, chronic atrophic gastritis by chronic superficial gastritis and report, General Hospital of PLA 6 hospital after 5 to 8 years of follow-up observation of 164 cases of superficial gastritis, including 34 cases into chronic atrophic gastritis (20.7%), etiology can chronic superficial gastritis become chronic atrophic gastritis pathogenesis and aggravating factors.
Genetic factors: (2) according to the Varis survey, patients with chronic atrophic gastritis of the first generation among relatives, chronic atrophic gastritis significantly increased the incidence of genetic factors, pernicious anemia is also very obvious, is related to the incidence rate is 20 times larger than the control group, chronic atrophic gastritis may be related to genetic factors.
(3) metal contact: lead the incidence of gastric ulcer workers operation rate is high, the gastric mucosa biopsy found atrophic gastritis incidence also increased, Polmer called the excretion of gastritis, except Pb many heavy metals such as mercury, tellurium, copper and zinc have certain effect on gastric mucosal injury.
(4) radiation: radiation therapy, ulcers or other tumors can cause damage or even atrophy of the gastric mucosa.
(5) iron deficiency anemia: a lot of the fact that iron deficiency anemia associated with atrophic gastritis, 50 cases of Badanoch reported iron deficiency anemia, normal gastric mucosa, superficial gastritis and atrophic gastritis each accounted for 14%, 46% and 40%, but the mechanism that anaemia causes gastritis is unknown, some scholars think that gastritis is the primary disease, because of low acid gastritis induced by iron cannot absorb, or because of stomach bleeding resulting in anemia; the other is that the first because of the lack of body iron anemia, gastric mucosal update rate affected and prone to inflammation.
(6) biological factors: chronic infectious diseases such as hepatitis, tuberculosis and other effects on the stomach also attracted the attention of people, patients with chronic liver disease often have chronic gastritis symptoms and signs of gastric mucosa staining also confirmed the antigen antibody complex with the hepatitis B virus in patients with hepatitis B in the gastric mucosa, Ruijin hospital reported 91 cases of atrophy gastritis patients, 24 cases (26.4%) with chronic hepatitis, and chronic infectious disease especially in patients with chronic liver disease of the stomach is worthy of note.
(7) physical factors: clinical statistics showed that showed a significant positive correlation with the age of this disease, age, function of gastric mucous membrane resistance is poor, easily affected by external adverse factors caused by injury.
(8) bile or duodenal reflux due to pyloric sphincter dysfunction or gastric or duodenal anastomosis after bile liquid reflux to the stomach, and the damage of the gastric mucosal barrier, promote H? + and anti pepsin scattered to the mucosa and cause a series of pathological changes, resulting in chronic superficial gastritis and the development of chronic atrophic gastritis.
(9): immune factors in atrophic gastritis, especially gastric body gastritis with blood, gastric juice or pulp cells in mucosal atrophy, often can be found in parietal cell antibody or antibody, so that autoimmune reaction is related to the etiology of chronic atrophic gastritis, in recent years the minority of antral gastritis patients the gastrin secreting cell antibody, it is the special cell antibodies, Ig G, part of patients with atrophic gastritis in vitro lymphocyte transformation test and leukocyte migration inhibition test is abnormal, the cellular immune response has an important significance in occurrence of atrophic gastritis.
(10) of Helicobacter pylori (HP) infection: 1983 Australia scholar Marshall and Warren from patients with chronic gastritis and gastric antrum mucous layer of epithelial cells was isolated from the HP, since then many scholars have conducted a lot of experimental research on patients with chronic gastritis, develop HP in 60% to 90% of patients with chronic gastric inflammation in gastric mucosa then, find the degree of infection was positively correlated with the severity of gastric mucosal inflammation related to the HP, the 1986 World Gastroenterological Association eighth session has proposed a HP infection is an important cause of chronic gastritis.
These are the pathogenic factors of gastritis, we hope to help, we also develop good eating habits in daily life, to eat digestible nutritious food, do not eat cold, hard, spicy spicy food, do not drink, so that we can protect our stomach mucosa irritation, promote its recovery.
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