As the improvement of living standards now, many people are suffering from the problem of gastritis, consider with the eating habits, habits are related. Most young people are superficial gastritis, the elderly are mostly atrophic gastritis. These two kinds of gastritis is caused by a variety of factors, so what specific adverse factors can lead to the occurrence of gastritis it?
1, Helicobacter pylori infection: 1982 Marshall and Warren first isolated a micro-aerobic, catalase positive, with urease activity of Gram-negative spirochete, 3μm × 0.5μm size, was curved or S-shaped end of a 2 to 6 sheaths with sheaths. 95% of active gastritis has this bacterial infection, initially named as Campylobacter Microorganisms (CLO), later renamed pyramid pylori (pylobacter pylori), in 1989 according to its biochemical and morphological characteristics once again renamed Helicobacter pylori ( figure 1).
We confirmed that Hp in chronic active gastritis detection rate of 98% to 100%, indicating that chronic gastritis, especially chronic active gastritis and Hp infection is closely related. 1985 Marshall, 1987 Morris two themselves as a volunteer oral Hp caused acute gastritis, cured by antibiotics. 1987 Lam bert successfully established the animal model of Hp gastritis with suckling pig so that Hp has basically conformed to Koch's criteria for pathogens.
2, autoimmune response: rich in parietal cells of the gastric body and gastric mucosal atrophy of the main. Changes in immune function in the pathogenesis of chronic gastritis has been generally attention, atrophic gastritis, especially in patients with gastric gastritis blood, gastric juice or atrophic mucosa can be found in parietal cell antibodies; gastric atrophy with pernicious anemia in patients with blood found Internal factor antibodies, indicating that the autoimmune response may be the cause of certain chronic gastritis. But the incidence of gastritis in the process of whether there are immune factors involved, there is no conclusion.
In addition, atrophic gastritis of the gastric mucosa has diffuse lymphocyte infiltration, in vitro lymphoblastocyte transformation test and leukocyte
Mobile inhibition test abnormalities, suggesting that cellular immune response in the occurrence of atrophic gastritis may have important significance. Some autoimmune diseases such as chronic thyroiditis, hypothyroidism or hyperthyroidism, insulin-dependent diabetes mellitus, chronic adrenal insufficiency, etc. may be associated with chronic gastritis, suggesting that the disease may be related to immune response.
3, acute gastritis suffering from: acute gastritis, gastric mucosal lesions lasting or recurrent, can form a chronic gastritis.
4, irritating food and drugs: long-term use of the gastric mucosa has a strong stimulating diet and drugs, such as tea, spirits, spicy or salicylate drugs, or food is not fully chewed, rough food repeatedly damaged gastric mucosa , Or excessive smoking, tobacco acid directly caused by gastric mucosa. Some drugs such as salicylate, digitalis, phenylbutazone, indomethacin, Xin Ke Fen, etc. can cause chronic gastric mucosal damage.
5, duodenal fluid reflux: study found that patients with chronic gastritis due to pyloric sphincter dysfunction, often cause bile reflux, may be an important risk factor. Pigmentation of phospholipids and bile and pancreatic digestive enzymes together, can dissolve mucus, and damage the gastric mucosal barrier, prompting H + and pepsin anti-diffusion into the mucosa, and further cause damage. The resulting chronic gastritis is mainly in the antrum. Gastric anastomosis patients due to bile reflux caused by gastritis are very common. Peptic ulcer patients are almost associated with chronic gastric antrum, may be related to pyloric sphincter dysfunction. Nicotine in tobacco can make the pyloric sphincter relaxation, so long-term smokers can contribute to bile reflux caused by gastric antrum.
6, bile reflux; bile contains bile salt can damage the gastric mucosal barrier, so that the gastric acid in the hydrogen ions anti-diffuse into the gastric mucosa and cause inflammation.
7, X-ray irradiation: depth X-ray irradiation of the stomach, can cause gastric mucosal damage, resulting in gastritis.
8, the impact of other organ lesions: such as chronic, uremia, ulcerative, chronic inflammation of the oral pharynx can cause chronic gastritis.
9, the earth physical changes: such as changes in the environment, climate changes, if people can not adapt in a short time, can cause the nerve dysfunction of the stomach, gastric juice secretion and stomach movement is not coordinated, resulting in gastritis.
10, bad habits: long-term mental stress, life is not the law.
(1) irregular time, often stay up late or day and night reversed.
(2) eating time is not the law, often do not eat or Meng eat.
(3) like to eat directly from the refrigerator out of food.
(4) eat something hot and cold, there is no certain rhythm.
All of the above is the cause of gastritis may cause. So in the usual life which we must pay more attention to the habit of living to the law, eating habits to be light, because too many bad factors will lead to the occurrence of gastritis, we can do only their own life diet. Away from gastritis, from their own start.
We confirmed that Hp in chronic active gastritis detection rate of 98% to 100%, indicating that chronic gastritis, especially chronic active gastritis and Hp infection is closely related. 1985 Marshall, 1987 Morris two themselves as a volunteer oral Hp caused acute gastritis, cured by antibiotics. 1987 Lam bert successfully established the animal model of Hp gastritis with suckling pig so that Hp has basically conformed to Koch's criteria for pathogens.
2, autoimmune response: rich in parietal cells of the gastric body and gastric mucosal atrophy of the main. Changes in immune function in the pathogenesis of chronic gastritis has been generally attention, atrophic gastritis, especially in patients with gastric gastritis blood, gastric juice or atrophic mucosa can be found in parietal cell antibodies; gastric atrophy with pernicious anemia in patients with blood found Internal factor antibodies, indicating that the autoimmune response may be the cause of certain chronic gastritis. But the incidence of gastritis in the process of whether there are immune factors involved, there is no conclusion.
In addition, atrophic gastritis of the gastric mucosa has diffuse lymphocyte infiltration, in vitro lymphoblastocyte transformation test and leukocyte
Mobile inhibition test abnormalities, suggesting that cellular immune response in the occurrence of atrophic gastritis may have important significance. Some autoimmune diseases such as chronic thyroiditis, hypothyroidism or hyperthyroidism, insulin-dependent diabetes mellitus, chronic adrenal insufficiency, etc. may be associated with chronic gastritis, suggesting that the disease may be related to immune response.
3, acute gastritis suffering from: acute gastritis, gastric mucosal lesions lasting or recurrent, can form a chronic gastritis.
4, irritating food and drugs: long-term use of the gastric mucosa has a strong stimulating diet and drugs, such as tea, spirits, spicy or salicylate drugs, or food is not fully chewed, rough food repeatedly damaged gastric mucosa , Or excessive smoking, tobacco acid directly caused by gastric mucosa. Some drugs such as salicylate, digitalis, phenylbutazone, indomethacin, Xin Ke Fen, etc. can cause chronic gastric mucosal damage.
5, duodenal fluid reflux: study found that patients with chronic gastritis due to pyloric sphincter dysfunction, often cause bile reflux, may be an important risk factor. Pigmentation of phospholipids and bile and pancreatic digestive enzymes together, can dissolve mucus, and damage the gastric mucosal barrier, prompting H + and pepsin anti-diffusion into the mucosa, and further cause damage. The resulting chronic gastritis is mainly in the antrum. Gastric anastomosis patients due to bile reflux caused by gastritis are very common. Peptic ulcer patients are almost associated with chronic gastric antrum, may be related to pyloric sphincter dysfunction. Nicotine in tobacco can make the pyloric sphincter relaxation, so long-term smokers can contribute to bile reflux caused by gastric antrum.
6, bile reflux; bile contains bile salt can damage the gastric mucosal barrier, so that the gastric acid in the hydrogen ions anti-diffuse into the gastric mucosa and cause inflammation.
7, X-ray irradiation: depth X-ray irradiation of the stomach, can cause gastric mucosal damage, resulting in gastritis.
8, the impact of other organ lesions: such as chronic, uremia, ulcerative, chronic inflammation of the oral pharynx can cause chronic gastritis.
9, the earth physical changes: such as changes in the environment, climate changes, if people can not adapt in a short time, can cause the nerve dysfunction of the stomach, gastric juice secretion and stomach movement is not coordinated, resulting in gastritis.
10, bad habits: long-term mental stress, life is not the law.
(1) irregular time, often stay up late or day and night reversed.
(2) eating time is not the law, often do not eat or Meng eat.
(3) like to eat directly from the refrigerator out of food.
(4) eat something hot and cold, there is no certain rhythm.
All of the above is the cause of gastritis may cause. So in the usual life which we must pay more attention to the habit of living to the law, eating habits to be light, because too many bad factors will lead to the occurrence of gastritis, we can do only their own life diet. Away from gastritis, from their own start.
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